Caveolin 1 Rabbit Polyclonal Antibody

Caveolin 1 Rabbit Polyclonal Antibody

规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,IHC-P,ICC/IF

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CAV1
SKU: APRab00005 Category: 兔多克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

Caveolin 1 Rabbit Polyclonal Antibody

描述(Description)

Rabbit polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

纯化方式(Purification)

Affinity Chromatography

 

免疫原

基因名(Gene Name)

CAV1

别名(Alternative Names)

CAV1; CAV; Caveolin-1

基因ID(Gene ID)

857

蛋白ID(SwissProt ID)

Q03135

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200

蛋白分子量(Molecular Weight)

Calculated MW: 20 kDa; Observed MW: 25 kDa

 

研究背景

Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

 

研究领域

Cardiovascular


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