Phospho-MSK1 (Ser376) Rabbit Polyclonal Antibody

Phospho-MSK1 (Ser376) Rabbit Polyclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,ICC/IF,IP

种属(Reactivity):Human,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):RPS6KA5
SKU: APRab00698 Category: 兔多克隆抗体 Tags: , , , , , , , ,

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产品概述

产品名称(Product Name)

Phospho-MSK1 (Ser376) Rabbit Polyclonal Antibody

描述(Description)

Rabbit polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF,IP

种属反应性(Reactivity)

Human,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

纯化方式(Purification)

Affinity Chromatography

 

免疫原

基因名(Gene Name)

RPS6KA5

别名(Alternative Names)

RPS6KA5; MSK1; Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL

基因ID(Gene ID)

9252

蛋白ID(SwissProt ID)

O75582

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW: 90 kDa; Observed MW: 90 kDa

 

研究背景

Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.

 

研究领域

Signal Transduction


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