| 产品名称 |
Recombinant Human NDRG1 (N-6His) |
| 英文名称 |
NDRG1/N-myc downstream-regulated gene 1 protein/NDRG1 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human N-myc Downstream Regulated Gene 1 is produced by our E.coli expression system and the target gene encoding Met1-Cys394 is expressed with a 6His tag at the N-terminus. |
| Accession |
Q92597 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
45 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Protein NDRG1; Differentiation-Related Gene 1 Protein; DRG-1; N-myc Downstream-Regulated Gene 1 Protein; Nickel-Specific Induction Protein Cap43; Reducing Agents and Tunicamycin-Responsive Protein; RTP; Rit42; NDRG1; CAP43; DRG1; RTP |
| 背景介绍 |
| Protein NDRG1 is a member of the N-Myc Downregulated Gene family, which is part of the α/β Hydrolase superfamily. Protein NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth and differentiation. Protein NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Protein NDRG1 mutuations are reported to be the cause for hereditary motor and sensory neuropathy-Lom. Decreased NDRG1 expression in glioma is linked to tumor progression; overexpression of NDRG1 is connected to malignant status of esophageal cancer. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
