GRP94 (2K1) Rabbit Monoclonal Antibody

GRP94 (2K1) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,ICC/IF,FC,IP,IF-P

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):HSP90B1
SKU: AMRe11798 Category: 兔单克隆抗体 Tags: , , , , , , , , , , ,

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产品概述

产品名称(Product Name)

GRP94 (2K1) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF,FC,IP

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

HSP90B1

别名(Alternative Names)

Endoplasmin; GRP-94; gp96 homolog; HSP90B1; GRP 94; TRA1;

基因ID(Gene ID)

7184

蛋白ID(SwissProt ID)

P14625

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000,IHC 1:1000-1:5000,ICC/IF 1:500-1:1000,FC 1:200-1:500,IP 1:20-1:50

蛋白分子量(Molecular Weight)

92kDa

 

研究背景

Molecular chaperone that functions in the processing and transport of secreted proteins. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD) (PubMed:18264092). Has ATPase activity (By similarity). May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum- Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (PubMed:32272059).

 

研究领域


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