Tyrosine Hydroxylase (14U19) Rabbit Monoclonal Antibody

Tyrosine Hydroxylase (14U19) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,ICC/IF

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):TH
SKU: AMRe19472 Category: 兔单克隆抗体 Tags: , , , , , , , ,

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产品概述

产品名称(Product Name)

Tyrosine Hydroxylase (14U19) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% protective protein.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

TH

别名(Alternative Names)

EC 1.14.16.2; TH isoform 3; TH isoform a; TH-4; TY3H; TYH; Tyrosine 3-hydroxylase; Tyrosine 3-monooxygenase; tyrosine hydroxylase;

基因ID(Gene ID)

7054

蛋白ID(SwissProt ID)

P07101

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:100-1:200

蛋白分子量(Molecular Weight)

58kDa

 

研究背景

Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the synthesis of the neurotransmitter dopamine and other catecholamines. TH functions as a tetramer, with each subunit composed of a regulatory and catalytic domain, and exists in several different isoforms. This enzyme is required for embryonic development since TH knockout mice die before or at birth. Plays an important role in the physiology of adrenergic neurons (By similarity). Positively regulates the regression of retinal hyaloid vessels during postnatal development (By similarity).

 

研究领域

Neuroscience


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