Securin Rabbit Polyclonal Antibody

Securin Rabbit Polyclonal Antibody

规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,IHC-P,ICC/IF,FC,IP

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):PTTG1
SKU: APRab00269 Category: 兔多克隆抗体 Tags: , , , , , , , ,

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产品概述

产品名称(Product Name)

Securin Rabbit Polyclonal Antibody

描述(Description)

Rabbit Polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC-P,ICC/IF,FC,IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

纯化方式(Purification)

Affinity Chromatography

 

免疫原

基因名(Gene Name)

PTTG1

别名(Alternative Names)

PTTG1; EAP1; PTTG; TUTR1; Securin; Esp1-associated protein; Pituitary tumor-transforming gene 1 protein; Tumor-transforming protein 1; hPTTG

基因ID(Gene ID)

9232

蛋白ID(SwissProt ID)

O95997/Q6IAL9

 

产品应用

稀释比(Dilution Ratio)

WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20 FC: 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW: 22 kDa; Observed MW: 28 kDa

 

研究背景

Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.

 

研究领域

Cell Biology


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