Rab7B Rabbit Monoclonal Antibody

Rab7B Rabbit Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):RAB7B
SKU: AMRe02509 Category: 兔单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

Rab7B Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

RAB7B

别名(Alternative Names)

RAB7

基因ID(Gene ID)

338382

蛋白ID(SwissProt ID)

Q96AH8

 

产品应用

稀释比(Dilution Ratio)

WB: 1:500-1:1000

蛋白分子量(Molecular Weight)

Calculated MW: 23 kDa; Observed MW: 23 kDa

 

研究背景

Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.

 

研究领域

Tags & Cell Markers


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