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产品应用
研究背景
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.
研究领域