EpCAM (15A7) Rabbit Monoclonal Antibody

EpCAM (15A7) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,IF-P

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):EPCAM
SKU: AMRe10506 Category: 兔单克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

EpCAM (15A7) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,IF-P

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

EPCAM

别名(Alternative Names)

Epithelial cell adhesion molecule; Ep-CAM; CO17A; CD326; Cell surface glycoprotein Trop-1; EGP; Epithelial glycoprotein 314; EGP314; hEGP314; KS 1/4 antigen; KSA;

基因ID(Gene ID)

4072

蛋白ID(SwissProt ID)

P16422

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:5000,IHC 1:100-1:200,IF-P 1:100-1:200

蛋白分子量(Molecular Weight)

35kDa

 

研究背景

Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+ independent, homophilic adhesions on the basolateral surface of most epithelial cells. The antigen is being used as a target for immunotherapy treatment of human carcinomas. May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

 

研究领域

Tags & Cell Markers


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