LDL Receptor (14L10) Rabbit Monoclonal Antibody

LDL Receptor (14L10) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,ICC/IF,FC,IF-P

种属(Reactivity):Human,Mouse
偶联物(Conjugate):Unconjugated
基因名(Gene Name):LDLR
SKU: AMRe13267 Category: 兔单克隆抗体 Tags: , , , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

LDL Receptor (14L10) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF,FC

种属反应性(Reactivity)

Human,Mouse

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

LDLR

别名(Alternative Names)

FH ; FHC ; LDL receptor; LDLCQ2; LDLR ; Low Density Lipoprotein Receptor; Low density lipoprotein receptor class A domain containing protein 3;

基因ID(Gene ID)

3949

蛋白ID(SwissProt ID)

P01130

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:20-1:100,FC 1:20-1:50

蛋白分子量(Molecular Weight)

95kDa

 

研究背景

Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.

 

研究领域


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