Angiotensinogen (15J4) Rabbit Monoclonal Antibody

Angiotensinogen (15J4) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,ICC/IF,IP

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):AGT
SKU: AMRe06889 Category: 兔单克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

Angiotensinogen (15J4) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,ICC/IF,IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

AGT

别名(Alternative Names)

Angiotensinogen; Serpin A8; AGT; SERPINA8; Des-Asp[1]-angiotensin II; Serine (or cysteine) proteinase inhibitor;

基因ID(Gene ID)

183

蛋白ID(SwissProt ID)

P01019

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:5000,ICC/IF 1:100-1:200,IP 1:10-1:100

蛋白分子量(Molecular Weight)

53kDa

 

研究背景

Angiotensin is formed from a precursor, angiotensinogen, which is produced by the liver and found in the a-globulin fraction of plasma. Angiotensin stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by co-immunoprecipitation. Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.

 

研究领域

Cardiovascular


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