EGFR Rabbit Monoclonal Antibody

EGFR Rabbit Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,IP

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):EGFR
SKU: AMRe04076 Category: 兔单克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

EGFR Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

EGFR

别名(Alternative Names)

EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

基因ID(Gene ID)

1956

蛋白ID(SwissProt ID)

P00533

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW: 134 kDa; Observed MW: 175 kDa

 

研究背景

EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

 

研究领域

Signal Transduction


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