CDKN2A/p16INK4a Rabbit Monoclonal Antibody

CDKN2A/p16INK4a Rabbit Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,ICC/IF,IP

种属(Reactivity):Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Cdkn2A
SKU: AMRe01812 Category: 兔单克隆抗体 Tags: , , , , , , ,

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产品概述

产品名称(Product Name)

CDKN2A/p16INK4a Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,ICC/IF,IP

种属反应性(Reactivity)

Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Cdkn2A

别名(Alternative Names)

Cdkn2a;P16ink4a;Cyclin-dependent kinase 4 inhibitor A (CDK4I);p16-INK4a ;p16-INK4

基因ID(Gene ID)

12578

蛋白ID(SwissProt ID)

P51480

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW: 18 kDa; Observed MW: 18 kDa

 

研究背景

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.CautionThe proteins described here are encoded by the gene CDKN2A, but are completely unrelated in terms of sequence and function to tumor suppressor ARF (AC Q64364) which is encoded by the same gene.

 

研究领域

Cell Biology


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