CDC7 Rabbit Monoclonal Antibody

CDC7 Rabbit Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IP

种属(Reactivity):Human,Hamster
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CDC7
SKU: AMRe01804 Category: 兔单克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

CDC7 Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IP

种属反应性(Reactivity)

Human,Hamster

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

CDC7

别名(Alternative Names)

Cell division cycle 7-related protein kinase; EC 2.7.11.1; CDC7-related kinase; HsCdc7; huCdc7; CDC7; CDC7L1; Hsk1; CDC7 kinase

基因ID(Gene ID)

8317

蛋白ID(SwissProt ID)

O00311

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IP 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW: 64 kDa; Observed MW: 64 kDa

 

研究背景

DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins).

 

研究领域

Cell Biology


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