Phospho-PML Protein (Ser518) Rabbit Monoclonal Antibody

Phospho-PML Protein (Ser518) Rabbit Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):PML
SKU: AMRe02867 Category: 兔单克隆抗体 Tags: , , , , ,

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产品概述

产品名称(Product Name)

Phospho-PML Protein (Ser518) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

PML

别名(Alternative Names)

PML; MYL; RNF71; TRIM19; Protein PML; Promyelocytic leukemia protein; RING finger protein 71; Tripartite motif-containing protein 19

基因ID(Gene ID)

5371

蛋白ID(SwissProt ID)

P29590

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW: 98 kDa; Observed MW: 98,117 kDa

 

研究背景

Regulates RB1 phosphorylation and activity. Required for normal development of the brain cortex during embryogenesis. Can sequester herpes virus and varicella virus proteins inside PML bodies, and thereby inhibit the formation of infectious viral particles. Regulates phosphorylation of ITPR3 and plays a role in the regulation of calcium homeostasis at the endoplasmic reticulum (By similarity). Regulates transcription activity of ELF4.

 

研究领域

Epigenetics and Nuclear Signaling


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