Phospho-ATP Citrate Synthase (Thr447/Ser451) Rabbit Monoclonal Antibody

Phospho-ATP Citrate Synthase (Thr447/Ser451) Rabbit Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):ACLY
SKU: AMRe01694 Category: 兔单克隆抗体 Tags: , , , ,

说明书 复制

产品概述

产品名称(Product Name)

Phospho-ATP Citrate Synthase (Thr447/Ser451) Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

ACLY

别名(Alternative Names)

ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme

基因ID(Gene ID)

47

蛋白ID(SwissProt ID)

P53396

 

产品应用

稀释比(Dilution Ratio)

WB: 1:500-1:1000

蛋白分子量(Molecular Weight)

Calculated MW: 121 kDa; Observed MW: 121 kDa

 

研究背景

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.

 

研究领域

Signal Transduction


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