JAK2 (6B4) Mouse Monoclonal Antibody

JAK2 (6B4) Mouse Monoclonal Antibody

规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):IHC-P

种属(Reactivity):Human,Rat,Mouse
偶联物(Conjugate):Unconjugated
基因名(Gene Name):JAK2
SKU: AMM00767 Category: 鼠单克隆抗体 Tags: , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

JAK2 (6B4) Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

IHC

种属反应性(Reactivity)

Human,Rat,Mouse

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

JAK2

别名(Alternative Names)

JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2

基因ID(Gene ID)

3717

蛋白ID(SwissProt ID)

O60674

 

产品应用

稀释比(Dilution Ratio)

IHC 1:50-1:100

蛋白分子量(Molecular Weight)

-

 

研究背景

Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.

 

研究领域

Cell Biology


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