MBD2 Mouse Monoclonal Antibody

MBD2 Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC

种属(Reactivity):Human, Mouse, Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):MBD2
SKU: AMM86088 Category: 鼠单克隆抗体 Tags: , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

MBD2 Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,IHC

种属反应性(Reactivity)

Human, Mouse, Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

MBD2

别名(Alternative Names)

Methyl-CpG-binding domain protein 2, Demethylase, DMTase, Methyl-CpG-binding protein MBD2, MBD2

基因ID(Gene ID)

8932

蛋白ID(SwissProt ID)

Q9UBB5

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:2000,IHC 1:100-1:500

蛋白分子量(Molecular Weight)

43.3kDa

 

研究背景

Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.

 

研究领域


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