KANK1 Mouse Monoclonal Antibody-EnkiLife

KANK1 Mouse Monoclonal Antibody

规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB,IHC
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：KANK1 SKU: AMM86076 Category: 鼠单克隆抗体 Tags: Mouse, Unconjugated, WB, IHC, Human

说明书复制

产品概述

产品名称（Product Name）	KANK1 Mouse Monoclonal Antibody
描述（Description）	Mouse monoclonal Antibody
宿主（Host）	Mouse
应用（Application）	WB,IHC
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	Mouse IgG1
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Purified antibody in PBS with 0.05% sodium azide.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	KANK1
别名（Alternative Names）	KN motif and ankyrin repeat domain-containing protein 1, Ankyrin repeat domain-containing protein 15, Kidney ankyrin repeat-containing protein, KANK1, ANKRD15, KANK, KIAA0172
基因ID（Gene ID）	23189
蛋白ID（SwissProt ID）	Q14678

产品应用

稀释比（Dilution Ratio）	WB 1:1000-1:2000,IHC 1:100-1:500
蛋白分子量（Molecular Weight）	147.3kDa

研究背景

Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity; the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia; the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading; the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.

研究领域