MITF Mouse Monoclonal Antibody

MITF Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC

种属(Reactivity):Human, Mouse, Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):MITF
SKU: AMM86015 Category: 鼠单克隆抗体 Tags: , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

MITF Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,IHC

种属反应性(Reactivity)

Human, Mouse, Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

MITF

别名(Alternative Names)

Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32, MITF, BHLHE32

基因ID(Gene ID)

4286

蛋白ID(SwissProt ID)

O75030

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:2000,IHC 1:500-1:2000

蛋白分子量(Molecular Weight)

58.8kDa

 

研究背景

Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'- CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

 

研究领域


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