产品概述
产品性能
免疫原
产品应用
研究背景
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
研究领域
Apoptosis,TGF-beta signaling pathway,PI3K-Akt signaling pathway,mTOR signaling pathway,MAPK signaling pathway,Jak-STAT signaling pathway
