WDR5 Mouse Monoclonal Antibody

WDR5 Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,ELISA

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):WDR5
SKU: AMM80866 Category: 鼠单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

WDR5 Mouse Monoclonal Antibody

描述(Description)

Mouse Monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,ELISA

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG2b

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Ascitic fluid containing 0.03% sodium azide.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

WDR5

别名(Alternative Names)

SWD3; BIG-3; WDR5

基因ID(Gene ID)

11091

蛋白ID(SwissProt ID)

P61964

 

产品应用

稀释比(Dilution Ratio)

WB:1:500-1:2000,ELISA:1:10000

蛋白分子量(Molecular Weight)

36.6kDa

 

研究背景

WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.

 


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