Upa Rabbit Monoclonal Antibody

Upa Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, ICC/IF

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Upa
SKU: AMRe87816 Category: 兔单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

Upa Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB, ICC/IF

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Upa

别名(Alternative Names)

ATF; QPD; UPA; URK; u-PA; BDPLT5

基因ID(Gene ID)

5328

蛋白ID(SwissProt ID)

P00749

 

产品应用

稀释比(Dilution Ratio)

WB: 1:1000-1:5000 ICC/IF: 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW:49 kDa; Observed MW:49 kDa

 

研究背景

This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

 


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