PCGF6 Rabbit Monoclonal Antibody

PCGF6 Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, ICC/IF, IP

种属(Reactivity):Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):PCGF6
SKU: AMRe87596 Category: 兔单克隆抗体 Tags: , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

PCGF6 Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB, ICC/IF, IP

种属反应性(Reactivity)

Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

PCGF6

别名(Alternative Names)

MBLR; Rnf134; AI604840; 4933407A11Rik

基因ID(Gene ID)

71041

蛋白ID(SwissProt ID)

Q99NA9

 

产品应用

稀释比(Dilution Ratio)

WB: 1:1000 ICC/IF: 1:100 IP: 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW:40 kDa; Observed MW:40 kDa

 

研究背景

Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.

 


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