Phospho-SIRT1 (Thr530) Rabbit Monoclonal Antibody

Phospho-SIRT1 (Thr530) Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Phospho-SIRT1
SKU: AMRe87109 Category: 兔单克隆抗体 Tags: , , ,

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产品概述

产品名称(Product Name)

Phospho-SIRT1 (Thr530) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Phospho-SIRT1

别名(Alternative Names)

SIR2; SIR2L1; SIR2alpha

基因ID(Gene ID)

23411

蛋白ID(SwissProt ID)

Q96EB6

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:5000

蛋白分子量(Molecular Weight)

Calculated MW:82 kDa; Observed MW:120 kDa

 

研究背景

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

 

研究领域


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