RUNX3 Rabbit Monoclonal Antibody

RUNX3 Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, IHC-P, IP

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):RUNX3
SKU: AMRe86839 Category: 兔单克隆抗体 Tags: , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

RUNX3 Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB, IHC-P, IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

RUNX3

别名(Alternative Names)

AML2; CBFA3; PEBP2aC

基因ID(Gene ID)

864

蛋白ID(SwissProt ID)

Q13761

 

产品应用

稀释比(Dilution Ratio)

WB: 1:1000 IHC-P: 1:500-1:2000 IP: 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW:44,46 kDa; Observed MW:44,46 kDa

 

研究背景

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

 


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