Thrombopoietin Rabbit Monoclonal Antibody

Thrombopoietin Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, IHC-P, ICC/IF, FC

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Thrombopoietin
SKU: AMRe86620 Category: 兔单克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

Thrombopoietin Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB, IHC-P, ICC/IF, FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Thrombopoietin

别名(Alternative Names)

ML; TPO; MGDF; MKCSF; MPLLG; THCYT1

基因ID(Gene ID)

7066

蛋白ID(SwissProt ID)

P40225

 

产品应用

稀释比(Dilution Ratio)

WB: 1:1000-1:5000 IHC-P: 1:500-1:2000 ICC/IF: 1:50 FC: 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW:38 kDa; Observed MW:38 kDa

 

研究背景

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]

 


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