NTH1 Rabbit Monoclonal Antibody

NTH1 Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,ICC

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):NTH1
SKU: AMRe85872 Category: 兔单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

NTH1 Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,ICC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

NTH1

别名(Alternative Names)

FAP3; NTH1; OCTS3; hNTH1

基因ID(Gene ID)

4913

蛋白ID(SwissProt ID)

P78549

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,ICC 1:50-1:200

蛋白分子量(Molecular Weight)

Calculated MW: 34 kDa; Observed MW: 34 kDa

 

研究背景

Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.

 

研究领域


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