| 产品名称 |
Recombinant Mouse RANK L V2 |
| 英文名称 |
RANK L |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<0.01 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Mouse Tumor necrosis factor ligand superfamily member 11 is produced by our Mammalian expression system and the target gene encoding Lys158-Asp316 is expressed with a 6His,Flag tag at the N-terminus. |
| Accession |
O35235-1 |
| 表达宿主 |
Human cells |
| 种属 |
Mouse |
| 预测分子量 |
23 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM His-HCl,100mM NaCl,10% Trehalose,0.05% Tween80, pH5.5 |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
0 |
| 分子别名 |
| Tumor necrosis factor ligand superfamily member 11;Tnfsf11;Osteoclast differentiation factor;ODF;Osteoprotegerin ligand;OPGL;Receptor activator of nuclear factor kappa-B ligand;RANKL;TNF-related activation-induced cytokine;TRANCE;CD254 |
| 背景介绍 |
| Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
