| 产品名称 |
Recombinant Rat IL-2 (C-6His) |
| 英文名称 |
IL-2/Interleukin-2/T cell growth factor/TCGF |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Rat Interleukin-2 is produced by our Mammalian expression system and the target gene encoding Ala21-Gln155 is expressed with a 6His tag at the C-terminus. |
| Accession |
P17108 |
| 表达宿主 |
Human Cells |
| 种属 |
Rat |
| 预测分子量 |
16.3 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 5mM NaH2POsub//u003E4/sub//u003E, 5mM Citric acid, 150mM NaCl, pH 4.0. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
0 |
| 分子别名 |
| Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin; IL2 |
| 背景介绍 |
| Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
