Granzyme B Rabbit Monoclonal antibody

Granzyme B Rabbit Monoclonal antibody

规格:50μL 价格:¥1500
规格:100μL 价格:¥2400
应用(Application):WB,IHC,IF,IP,ELISA

种属(Reactivity):Human,
偶联物(Conjugate):Unconjugated
基因名(Gene Name):GZMB CGL1 CSPB CTLA1 GRB
SKU: AMRe21246 Category: 兔单克隆抗体 Tags: , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

Granzyme B Rabbit Monoclonal antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,IF,IP,ELISA

种属反应性(Reactivity)

Human,

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG,Kappa

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化方式(Purification)

Protein A

 

免疫原

基因名(Gene Name)

GZMB CGL1 CSPB CTLA1 GRB

别名(Alternative Names)

Granzyme B;C11;CTLA-1;Cathepsin G-like 1;CTSGL1;Cytotoxic T-lymphocyte proteinase 2;Lymphocyte protease;Fragmentin-2;Granzyme-2;Human lymphocyte protein;HLP;SECT;T-cell serine protease 1-3E;

基因ID(Gene ID)

3002

蛋白ID(SwissProt ID)

P10144

 

产品应用

稀释比(Dilution Ratio)

IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

蛋白分子量(Molecular Weight)

Calculated MW:28kD;Observed MW:37kD

 

研究背景

Cell localization:Lysosome.This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016],

 

研究领域


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