ICOS (16D3) Rabbit Monoclonal Antibody

ICOS (16D3) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,IP

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):ICOS
SKU: AMRe12341 Category: 兔单克隆抗体 Tags: , , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

ICOS (16D3) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,IP

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

ICOS

别名(Alternative Names)

AILIM; CD278; CRP1; CVID1; ICOS;

基因ID(Gene ID)

29851

蛋白ID(SwissProt ID)

Q9Y6W8

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000,IHC 1:200-1:500,IP 1:20-1:50

蛋白分子量(Molecular Weight)

23kDa

 

研究背景

Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin- 2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40- mediated class switching of immunoglobin isotypes (By similarity).

 

研究领域

Cell adhesion molecules (CAMs);T_Cell_Receptor;Intestinal immune network for IgA production;Primary immunodeficiency;


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