S100 alpha 6 (12M1) Rabbit Monoclonal Antibody

S100 alpha 6 (12M1) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,ICC/IF,IF-P

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):S100A6
SKU: AMRe17461 Category: 兔单克隆抗体 Tags: , , , , , , ,

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产品概述

产品名称(Product Name)

S100 alpha 6 (12M1) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

S100A6

别名(Alternative Names)

Protein S100-A6; Calcyclin; MLN 4; PRA; CACY; CABP; 5B10;

基因ID(Gene ID)

6277

蛋白ID(SwissProt ID)

P06703

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000,IHC 1:50-1:100,ICC/IF 1:200-1:500

蛋白分子量(Molecular Weight)

10kDa

 

研究背景

S100A6 (calcyclin) is involved in a number of cellular processes, including exocytosis and cell cycle regulation. In addition, S100A6 interacts with a number of proteins such as SIP, GAPDH, and annexins in a calcium-dependent fashion. Research studies demonstrate that a down regulation of corresponding S100A6 gene expression causes a decrease in cell proliferation. May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.

 

研究领域

Cell Biology


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