TPMT (3H2) Rabbit Monoclonal Antibody

TPMT (3H2) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,FC

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):TPMT
SKU: AMRe19157 Category: 兔单克隆抗体 Tags: , , , , , , , ,

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产品概述

产品名称(Product Name)

TPMT (3H2) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,FC

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% protective protein.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

TPMT

别名(Alternative Names)

Thiopurine methyltransferase; TPMT;

基因ID(Gene ID)

7172

蛋白ID(SwissProt ID)

P51580

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:5000,IHC 1:100-1:200,FC 1:100-1:500

蛋白分子量(Molecular Weight)

28kDa

 

研究背景

Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine. Catalyzes the S-methylation of thiopurine drugs such as 6- mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S- adenosyl-L-methionine as the methyl donor (PubMed:657528, PubMed:18484748). TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural substrate for this enzyme has yet to be identified.

 

研究领域

Signal Transduction


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