CD276 Mouse Monoclonal Antibody

CD276 Mouse Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,IHC,IF,FlowCyt,ELISA

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CD276
SKU: AMM20427 Category: 鼠单克隆抗体 Tags: , , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

CD276 Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,IHC,ICC/IF,ELISA,FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

CD276

别名(Alternative Names)

CD276 ;B7H3 ;PSEC0249 ;CD276 antigen ;4Ig-B7-H3 ;B7 homolog 3 ;B7-H3 ;Costimulatory molecule ;CD antigen CD276

基因ID(Gene ID)

80381

蛋白ID(SwissProt ID)

Q5ZPR3

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400

蛋白分子量(Molecular Weight)

Observed MW: 100 kDa

 

研究背景

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3'-UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

 

研究领域

Cell adhesion molecules


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