Phospho-BCAR1 (Y410) (17X7) Rabbit Monoclonal Antibody-EnkiLife

Phospho-BCAR1 (Y410) (17X7) Rabbit Monoclonal Antibody

规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：BCAR1 SKU: AMRe05859 Category: 兔单克隆抗体 Tags: Human, WB, Unconjugated, Rabbit, -

说明书复制

产品概述

产品名称（Product Name）	Phospho-BCAR1 (Y410) (17X7) Rabbit Monoclonal Antibody
描述（Description）	Recombinant rabbit monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Phosphorylated
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
纯化方式（Purification）	Affinity purification

免疫原

基因名（Gene Name）	BCAR1
别名（Alternative Names）	BCAR 1; Bcar1; Breast cancer anti estrogen resistance 1 Breast cancer anti-estrogen resistance protein 1; CAS; Cas scaffolding protein family member 1; CAS1; Cass1; Crk associated substrate; Crk associated substrate p130Cas; CRK-associated substrate; CRKAS; p130cas;
基因ID（Gene ID）	9564
蛋白ID（SwissProt ID）	P56945

产品应用

稀释比（Dilution Ratio）	WB 1:1000-1:5000
蛋白分子量（Molecular Weight）	93kDa

研究背景

Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells. Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion (PubMed:12832404, PubMed:12432078). Implicated in induction of cell migration and cell branching (PubMed:12432078, PubMed:12832404, PubMed:17038317). Involved in the BCAR3-mediated inhibition of TGFB signaling (By similarity).

研究领域

Signal Transduction; Protein Phosphorylation; Tyrosine Kinases; Cancer