C4 binding protein (14B18) Rabbit Monoclonal Antibody

C4 binding protein (14B18) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,ICC/IF,IP,IF-P

种属(Reactivity):Human,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):C4BPB
SKU: AMRe07750 Category: 兔单克隆抗体 Tags: , , , , , , , , ,

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产品概述

产品名称(Product Name)

C4 binding protein (14B18) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF,IP

种属反应性(Reactivity)

Human,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

C4BPB

别名(Alternative Names)

C4BP; C4BPB; PRP;

基因ID(Gene ID)

725

蛋白ID(SwissProt ID)

P20851

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200,IP 1:50-1:100

蛋白分子量(Molecular Weight)

28kDa

 

研究背景

Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.

 

研究领域

Immunology


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