SMC1A Mouse Monoclonal Antibody-EnkiLife

SMC1A Mouse Monoclonal Antibody

规格：50μL 价格：￥1200
规格：100μL 价格：￥2150
应用（Application）：WB,ICC/IF
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：SMC1A SKU: AMM00962 Category: 鼠单克隆抗体 Tags: Human, WB, ICC/IF, Unconjugated, Mouse, Cell Biology

说明书复制

产品概述

产品名称（Product Name）	SMC1A Mouse Monoclonal Antibody
描述（Description）	Mouse Monoclonal Antibody
宿主（Host）	Mouse
应用（Application）	WB,ICC/IF
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG1
克隆（Clonality）	Monoclonal Antibody
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	SMC1A
别名（Alternative Names）	Chromosome segregation protein SmcB; DXS423E; KIAA0178; MGC138332; Sb1.8; Segregation of mitotic chromosomes 1; SMC protein 1A; SMC-1-alpha; SMC-1A; SMC1 (structural maintenance of chromosomes 1 yeast) like 1; SMC1; SMC1 structural maintenance of chromosomes 1 like 1; SMC1A; SMC1A_HUMAN; SMC1alpha; SMC1L1; SMCB; Structural maintenance of chromosomes 1A; Structural maintenance of chromosomes protein 1A.
基因ID（Gene ID）	8243
蛋白ID（SwissProt ID）	Q14683

产品应用

稀释比（Dilution Ratio）	WB: 1:500-1:1000 IF: 1:50-1:200
蛋白分子量（Molecular Weight）	Calculated MW: 143 kDa; Observed MW: 143 kDa

研究背景

Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair . ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint. SMC1 phosphorylation is ATM-independent in cells subjected to other forms of DNA damage, including UV light and hydroxyurea treatment.

研究领域

Cell Biology

SMC1A Mouse Monoclonal Antibody

SMC1A Mouse Monoclonal Antibody

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