ERCC1 (7F6) Mouse Monoclonal Antibody

ERCC1 (7F6) Mouse Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):ERCC1
SKU: AMM03528 Category: 鼠单克隆抗体 Tags: , , , ,

说明书 复制

产品概述

产品名称(Product Name)

ERCC1 (7F6) Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG2b

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

ERCC1

别名(Alternative Names)

ERCC1; DNA excision repair protein ERCC-1

基因ID(Gene ID)

2067

蛋白ID(SwissProt ID)

P07992

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000

蛋白分子量(Molecular Weight)

Calculated MW: 33 kDa; Observed MW: 39 kDa

 

研究背景

DNA repair systems operate in all living cells to manage a variety of DNA lesions. Nucleotide excision repair (NER) is implemented in cases where bulky helix-distorting lesions occur, such as those brought about by UV and certain chemicals. Research studies have shown that expression of ERCC1 is related to survival rate and response to chemotherapeutic drugs in several human cancers including non-small cell lung cancer (NSCLC).

 

研究领域

Epigenetics and Nuclear Signaling


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