beta Arrestin 1 (6A1) Mouse Monoclonal Antibody-EnkiLife

beta Arrestin 1 (6A1) Mouse Monoclonal Antibody

规格：20μL 价格：￥600
规格：50μL 价格：￥1200
规格：100μL 价格：￥2150
应用（Application）：WB
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：ARRB1 SKU: AMM03464 Category: 鼠单克隆抗体 Tags: Human, WB, Unconjugated, Mouse, Signal Transduction

说明书复制

产品概述

产品名称（Product Name）	beta Arrestin 1 (6A1) Mouse Monoclonal Antibody
描述（Description）	Mouse monoclonal Antibody
宿主（Host）	Mouse
应用（Application）	WB
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG2b
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	ARRB1
别名（Alternative Names）	ARB1; ARR1; ARRB1; ARRB1_HUMAN; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1.
基因ID（Gene ID）	408
蛋白ID（SwissProt ID）	P49407

产品应用

稀释比（Dilution Ratio）	WB 1:500-1:1000
蛋白分子量（Molecular Weight）	Calculated MW: 47 kDa; Observed MW: 51 kDa

研究背景

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]

研究领域

Signal Transduction