AMPK alpha Rabbit Monoclonal Antibody

AMPK alpha Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IP

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):AMPK alpha
SKU: AMRe85224 Category: 兔单克隆抗体 Tags: , , , , , , ,

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产品概述

产品名称(Product Name)

AMPK alpha Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

AMPK alpha

别名(Alternative Names)

PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase

基因ID(Gene ID)

5563

蛋白ID(SwissProt ID)

P54646

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IP 1:10-1:20

蛋白分子量(Molecular Weight)

Calculated MW: 62 kDa; Observed MW: 62 kDa

 

研究背景

AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3). The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia, and ischemia.

 

研究领域

Autophagy,Wnt signaling pathway,PI3K-Akt signaling pathway


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