Phospho-PKR (Thr451) Rabbit Monoclonal Antibody

Phospho-PKR (Thr451) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Phospho-PKR (Thr451)
SKU: AMRe84876 Category: 兔单克隆抗体 Tags: , , ,

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产品概述

产品名称(Product Name)

Phospho-PKR (Thr451) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Phospho-PKR (Thr451)

别名(Alternative Names)

EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k

基因ID(Gene ID)

5610

蛋白ID(SwissProt ID)

P19525

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000

蛋白分子量(Molecular Weight)

Calculated MW: 62 kDa; Observed MW: 74 kDa

 

研究背景

PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.

 

研究领域


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