OCT3 Mouse Monoclonal Antibody

OCT3 Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,ELISA

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):OCT3
SKU: AMM80701 Category: 鼠单克隆抗体 Tags: , , , ,

说明书 复制

产品概述

产品名称(Product Name)

OCT3 Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

ELISA,FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

PBS containing 0.03% sodium azide.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

OCT3

别名(Alternative Names)

OCT3; OTF3; OTF4; MGC22487; POU5F1

基因ID(Gene ID)

5460

蛋白ID(SwissProt ID)

Q01860

 

产品应用

稀释比(Dilution Ratio)

ELISA 1:5000-1:20000,FC 1:200-1:400

蛋白分子量(Molecular Weight)

38.5kDa

 

研究背景

Oct4: octamer-binding transcription factor-4 (Oct-4, Otf-4) and Oct-3/4, also known as POU5F1(POU class 5 homeobox 1), octamerbinding transcription factor-3 (Oct-3, Otf-3), modulates embryonic stem (ES) cell populations by influencing lineage commitment. Entrez Protein NP_002692. Oct-3/4 sustains stem-cell selfrenewal and differentiation pathways. Transcription factors containing the POU homeodomain regulate tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development. Oct-3/4 is capable of inducing rapid proliferation and tumorigenic properties of ES cells through activation of the UTF1 gene. In humans, two Oct-3/4 isoforms contribute to influencing the undifferentiated phenotype of ES cells. Oct-3/4 pseudogenes localizing to human chromosomes 10 and 8 are reported to be transcribed in certain cancer cell lines and tissues.

 

研究领域


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