Dnmt1 Rabbit Monoclonal Antibody

Dnmt1 Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, IHC-P, ICC/IF, FC

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Dnmt1
SKU: AMRe86343 Category: 兔单克隆抗体 Tags: , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

Dnmt1 Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB, IHC-P, ICC/IF, FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Dnmt1

别名(Alternative Names)

AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN; m.HsaI

基因ID(Gene ID)

1786

蛋白ID(SwissProt ID)

P26358

 

产品应用

稀释比(Dilution Ratio)

WB: 1:1000-1:5000 IHC-P: 1:200-1:1000 ICC/IF: 1:100-1:200 FC: 1:20

蛋白分子量(Molecular Weight)

Calculated MW:183 kDa; Observed MW:183 kDa

 

研究背景

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

 


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