CDKN1B Mouse Monoclonal Antibody

CDKN1B Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CDKN1B
SKU: AMM85962 Category: 鼠单克隆抗体 Tags: , , , , ,

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产品概述

产品名称(Product Name)

CDKN1B Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,IHC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

CDKN1B

别名(Alternative Names)

Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1

基因ID(Gene ID)

1027

蛋白ID(SwissProt ID)

P46527

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000,IHC 1:100-1:500

蛋白分子量(Molecular Weight)

22.1kDa

 

研究背景

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

 

研究领域

PI3K-Akt signaling pathway


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