RET Mouse Monoclonal Antibody-EnkiLife

RET Mouse Monoclonal Antibody

规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB,IHC,ICC
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：RET SKU: AMM85912 Category: 鼠单克隆抗体 Tags: Mouse, Unconjugated, WB, IHC, ICC, Human

说明书复制

产品概述

产品名称（Product Name）	RET Mouse Monoclonal Antibody
描述（Description）	Mouse monoclonal Antibody
宿主（Host）	Mouse
应用（Application）	WB,IHC,ICC
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	Mouse IgM
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Purified antibody in PBS with 0.05% sodium azide.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	RET
别名（Alternative Names）	Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120 kDa fragment, RET, CDHF12, CDHR16, PTC, RET51
基因ID（Gene ID）	5979
蛋白ID（SwissProt ID）	P07949

产品应用

稀释比（Dilution Ratio）	WB 1:500-1:2000,IHC 1:100-1:500,ICC 1:20-1:50
蛋白分子量（Molecular Weight）	124.3kDa

研究背景

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.

研究领域