LEF1 Rabbit Monoclonal Antibody

LEF1 Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,ICC

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):LEF1
SKU: AMRe85748 Category: 兔单克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

LEF1 Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,ICC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

LEF1

别名(Alternative Names)

LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha

基因ID(Gene ID)

51176

蛋白ID(SwissProt ID)

Q9UJU2

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,ICC 1:50-1:200

蛋白分子量(Molecular Weight)

Calculated MW: 44 kDa; Observed MW: 25-58 kDa

 

研究背景

Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity).

 

研究领域

Wnt signaling pathway,Hippo signaling pathway


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