LXR alpha Rabbit Monoclonal Antibody

LXR alpha Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC

种属(Reactivity):Human,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):LXR alpha
SKU: AMRe85762 Category: 兔单克隆抗体 Tags: , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

LXR alpha Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC

种属反应性(Reactivity)

Human,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

LXR alpha

别名(Alternative Names)

NR1H3; LXRA; Oxysterols receptor LXR-alpha; Liver X receptor alpha; Nuclear receptor subfamily 1 group H member 3

基因ID(Gene ID)

10062

蛋白ID(SwissProt ID)

Q13133

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW: 50 kDa; Observed MW: 50 kDa

 

研究背景

Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.

 

研究领域


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