VAV1 Mouse Monoclonal Antibody

VAV1 Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,FC,ELISA

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):VAV1
SKU: AMM81156 Category: 鼠单克隆抗体 Tags: , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

VAV1 Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,ELISA,FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

VAV1

别名(Alternative Names)

VAV

基因ID(Gene ID)

7409

蛋白ID(SwissProt ID)

P15498

 

产品应用

稀释比(Dilution Ratio)

WB 1:250-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400

蛋白分子量(Molecular Weight)

98.3kDa

 

研究背景

The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.

 

研究领域


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