产品概述
产品性能
免疫原
产品应用
研究背景
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
研究领域
TGF-beta signaling pathway,PI3K-Akt signaling pathway,MAPK signaling pathway,Jak-STAT signaling pathway,Hippo signaling pathway
